Tag Archives: publications

Poonami and metagenomics

Sorry there’s not been many posts for a while. I entered a poonami. For those of you without children, that’s a technical biology term for when you’ve just finished changing one nappy (American: ‘diaper’) only to have another spurt out. … Continue reading

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Our Nature paper! Genome-wide molecular convergence in echolocating mammals

Exciting news from the lab this week… we’ve published in one of the leading journals, Nature!!! Much of my work in the Rossiter BatLab for the last couple of years has centred around the search for genomic signatures of molecular … Continue reading

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The mode and tempo of hepatitis C virus evolution within and among hosts.

BMC Evol Biol. 2011 May 19;11(1):131. [Epub ahead of print] Gray RR*, Parker J*, Lemey P, Salemi M, Katzourakis A, Pybus OG. *These authors contributed equally to this article. BACKGROUND: Hepatitis C virus (HCV) is a rapidly-evolving RNA virus that … Continue reading

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Generation of neutralizing antibodies and divergence of SIVmac239 in cynomolgus macaques following short-term early antiretroviral therapy.

PLoS Pathog. 2010 Sep 2;6(9):e1001084. Ozkaya Sahin G, Bowles EJ, Parker J, Uchtenhagen H, Sheik-Khalil E, Taylor S, Pybus OG, Mäkitalo B, Walther-Jallow L, Spångberg M, Thorstensson R, Achour A, Fenyö EM, Stewart-Jones GB, Spetz AL. Neutralizing antibodies (NAb) able … Continue reading

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Safety and immunogenicity of novel recombinant BCG and modified vaccinia virus Ankara vaccines in neonate rhesus macaques.

J Virol. 2010 Aug;84(15):7815-21. Epub 2010 May 19. Rosario M, Fulkerson J, Soneji S, Parker J, Im EJ, Borthwick N, Bridgeman A, Bourne C, Joseph J, Sadoff JC, Hanke T Although major inroads into making antiretroviral therapy available in resource-poor … Continue reading

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Full-Length Characterization of Hepatitis C Virus Subtype 3a Reveals Novel Hypervariable Regions under Positive Selection during Acute Infection

Humphreys I, Fleming V, Fabris P, Parker J, Schulenberg B, Brown A, Demetriou C, Gaudieri S, Pfafferott K, Lucas M, Collier J, Huang KH, Pybus OG, Klenerman P, Barnes E. J Virol. 2009 Nov;83(22):11456-66. Epub 2009 Sep 9. Hepatitis C … Continue reading

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The within- and among-host evolution of chronically-infecting human RNA viruses

A research thesis submitted for the degree of Doctor of Philosophy at the University of Oxford. J Parker Funded by: Natural Environment Research Council (UK) with support from Linacre College, Oxford. Abstract: This thesis examines the evolutionary biology of the … Continue reading

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Estimating the Date of Origin of An HIV-1 Circulating Recombinant Form

Virology. 2009 Apr 25;387(1):229-34. Epub 2009 Mar 9. Tee KK, Pybus OG, Parker J, Ng KP, Kamarulzaman A, Takebe Y. HIV is capable of frequent genetic exchange through recombination. Despite the pandemic spread of HIV-1 recombinants, their times of origin … Continue reading

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Correlating Viral Phenotypes With Phylogeny: Accounting for Phylogenetic Uncertainty

Infect Genet Evol. 2008 May;8(3):239-46. Epub 2007 Aug 21. Parker J, Rambaut A, Pybus OG. Many recent studies have sought to quantify the degree to which viral phenotypic characters (such as epidemiological risk group, geographic location, cell tropism, drug resistance … Continue reading

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