Category Archives: Blog

Dunwich Dynamo XIX

(n.b. Originally published in Bog & Pheasant, Aug 2011)

It is seven o’ clock on a Sunday morning in July, and I’m pedalling frantically down a muddy track in the middle of the East Anglian countryside. Next to me are a gang of escaped urban bike couriers on chunky, single-speed traffic hogs, while behind me a couple in long neon pink wigs drive their tandem remorselessly on. Ahead is the sea, and a cup of tea, and the knowledge that if I get there I’ll have joined a small but growing band of riders who can proudly say “I finished the Dunwich Dynamo”

The ‘Dun Run’ is a semi-organized 200km bike ride from Hackney to the beach at Dunwich, in Suffolk. Rumour has it that the annual event began around two decades ago, when a group of bored couriers decided on an after-work ride one summer evening. Having found a straight road through Epping Forest, they continued on for several hours until they hit the sea. After a brief spell as a timed, semi-professional race in the Nineties, the Dun Run has been a free event* open to all comers since 1999. Attendance at the legendary event grew with the mushrooming popularity of cycling in the capital: last year over 1,000 riders took part.

As I roll up to London Fields on Saturday night, it’s easy to believe that double that number have turned out this year, despite the torrential rain earlier in the day: a confusion of cyclists clog the fields and road with fluorescent pinks, oranges, greens and yellows. Cycling vests are on display, London’s Velo clubs out in force. Every type of cyclist is here – recumbents; tandems and tricycles; commuters; kids; fixies; racers and even one or two optimistic fold-up bikes**. Much lycra is on show, as well (having done London – Brighton quite a few times in my jeans I scoff at this).

After about an hour’s worth of gentle milling around in the fading light, and with no particular sense of occasion, helmets are donned, lights switched on, and we begin to wind our way through the city. Epping Forest looms quickly and soon we pick up speed. Crossing the M25 we’re suddenly in the middle of the countryside. Villages with strange names slip by, I join and leave a succession of mini-pelotons and time ticks on as an endless stream of blinking red lights snakes blindly on into the darkness.

A stop at a village hall 55 miles in provides an opportunity for soup, leg stretching, and the toilet. A volunteer team are feeding hundreds of hungry people, currently looking – and smelling – more like refugees than long-distance cycling champions. A few people succumb to the temptation to sleep, while their friends look on in mock disapproval. Gradually the rest stop empties out as people gird themselves to remount and finish the ride.

From here on in the ride is slower, and more social. The pack thins out, with only a few tens of riders visible at a time. We suddenly realise we have no idea where we are; luckily a recently-overtaken greybeard graciously shows us the way (with a wry smile). The roads become smaller, and smaller as the rising sun in front of us warms our spirits (if not our hands).

Finally I roll onto the beach just after 7.30. Exhausted but happy cyclists and bikes litter the ground like a colony of flopped-out penguins. I’ve won a sense of massive achievement and though I feel myself becoming addicted to this long-distance lark, I reflect later, sweating through another 30 miles to Ipswich train station, that maybe a pair of nice, padded Lycra pants might not be such a needless concession to fashion after all.

I should point out that the event is organised – for free – by the brilliant Southwark Cyclists. Chapeau!

One nutjob actually completed the whole thing on a Boris bike…

Community! Fusion

Love fundraisers.* Next month we’re taking part in one that’s a little bit different.

Community Fusion is a new charity venture in Portsmouth, a youth volunteering programme that aims to match young people to community projects. The volunteers benefit from personal development, learning and CV-worthy experience, while important, local, community-centred projects are helped and supported by those young people in the immediate area.

It’s a great scheme and one of the first projects is the regeneration of the Hilsea Lido complex. This iconic open-air pool opened in 1935 and quickly became a loved landmark and even featured a miniature railway at one stage. At the end of the last century however, it fell into disrepair. Step in the Hilsea Lido For The People trust, who purchased a 99-year lease on the pool from Portsmouth Council. They’re slowly but surely reviving the lido’s fortunes, refurbishing it and creating a social and cultural nexus for the whole community.

To mark this new collaboration and raise funds, there’s going to be a big family-friendly party / BBQ on Sunday 14th August. I’ll be playing with the band, as well as Huw Olesker, Luke Ferre and Hannah O’Reilly. There will also be face-painting, magic and apparently, sun. That’s the Blue Lagoon, Hilsea Lido, London Road, Portsmouth, Hants, PO2 9RP (Map). Doors are from 1pm – 6pm and I have no idea when we’re on yet (plus it’s a big ole party) so get there early!

*Anyway, here’s a quick video of Stewart Lee talking about charity (go to about 3:00 if you have a terminally short attention span):

The 2011 Twitter 1-Take Challenge

I was having a bit of an argy on Twitter with @jimmyhatherley (Moneytree) and @punchdrunkpaper (Thomas Tantrum) below. Cue songwriting frenzy. One go at every part, none of it written first.

Yes it is A MASSIVE LAME GRUNGE RIPOFF with particular apologies to Evan Dando ‘(The) Door’ and Sleeper ‘Alice In Vain’. OK, Sleeper aren’t even grunge. But then neither are Japanese Voyeurs (none of them are even a bit ugly).. And I beat Dave, which was the aim.

Since the whole point of the exercise was to insult them in the most throwaway demonstration of instant songwriting possible, here’s the lyrics (also jammed out as they went down):

Jimmy’s got a job and he likes it

So he’s keeping dumb about / The bankers, the cantankerous ones

He serves, he smiles and they don’t care

About his politics, positions and / His ethics and his current affairs

Jackie’s got a girl and he likes her

Four fingers and a thumb / Playing on his bum all day long

He might just sit there and lay there

His hair is getting greasier / His thighs are getting stickier / Papers piling up all around

So what about me, Lonely?

.. Urm.

Coda: The Argument:

@lonelyjoeparker: squier tele + holy stain + roost head + 4x12 + chords from 'a lover sings' = many happy wasted hours @punchdrunkpaper #GEmCAm

@PunchdrunkPaper @LonelyJoeParker glad to see you're still setting challenges for yourself on the guitar there joe #imacunt

@lonelyjoeparker: @PunchdrunkPaper woteva bra. if you could only half 'play' with the 'feel' the way i 'vibe' dat 'ting' you'd give up die happy

@lonelyjoeparker: @PunchdrunkPaper #notthesizeofurtalentbutwhatudowivit #pwn

@PunchdrunkPaper: @LonelyJoeParker get "stuffed"

@jimmyhatherley: @lonelyjoeparker @punchdrunkpaper stop squabbling and write some songs!

@lonelyjoeparker: @jimmyhatherley @punchdrunkpaper i'll write you

@PunchdrunkPaper: @jimmyhatherley @lonelyjoeparker good plan. i'll try and post a demo up later today ;)

@lonelyjoeparker: @PunchdrunkPaper @jimmyhatherley BEAT YOU http://www.lonelyjoeparker.com/?p=773 http://bit.ly/qO9S1y

Did I mention I’m available to write for hire? Seriously now. Yes.

A bit down; recording in my pants (Evan Dando)

Joe recordingRecorded in my pants this morning into garageband. No interface – straight in. Sorry for quietness.

… First heard this song on the B-side to ‘Outdoor Type’, recorded live for a radio station in Milan. It’s a really underrated Dando one I think; one of those that just flows out of you when that black dog calls.

LOSING YOUR MIND (Evan Dando; ASCAP)
====================================

What a comfort to find out you’re losing your mind / when you re-realise that it’s not the first time / burnt the beyond when you learned how to fly / just to learn later on that there isn’t a sky / there aren’t any clouds, and there aren’t any trees / and there aren’t any birds / and there’s no cinder caught in my eye / til I’ve tied a tired knot and tried to untie it / I can’t decide if I should lie / or tell the truth and try to hide it.

St John’s Wood

So.. in the last couple of weeks we have been recording vocals for the LP at a (fairly) secret (but let’s face it, well-known) location in north-west London. We’ve been dubbing onto the great instrumental tracks recorded at Furnace Studios in Bulgaria.

With James Ewers at the controls, free coffee, bubbly and fame cake, and guest appearances on BVs from Emma Richardson (Band of Skulls) and Alcxxk (Internet Forever – and he also did a wee bit of tromboning) it is sounding ACE.

Just got a few string bits and gang vocals to do now – going to Valley Studios in Winchester of this cos they’ve got a great feel there and we can piss about with real tape as well. Release will be sometime between October and next February. Keep an eye out for stuff on Soundcloud though…

EP News

In the meantime we will be releasing the Falmouth sessions very soon. This is a load of louder stuff recorded as Ann The Arc (Jimmy Shivers – bass; Dave Wade-Brown – drums) and produced by Dan Parry. Songs like ‘Hake’, ‘Wolf’ and yes, ‘Stutter’ plus a couple of others should make for a nice fat EP. Working title is ‘The Young Unprofessionals’ and we’re hoping Sotones will release it.

Think that’s all for now, bye x

The mode and tempo of hepatitis C virus evolution within and among hosts.

BMC Evol Biol. 2011 May 19;11(1):131. [Epub ahead of print]

Gray RR*, Parker J*, Lemey P, Salemi M, Katzourakis A, Pybus OG.

*These authors contributed equally to this article.

BACKGROUND:

Hepatitis C virus (HCV) is a rapidly-evolving RNA virus that establishes chronic infections in humans. Despite the virus’ public health importance and a wealth of sequence data, basic aspects of HCV molecular evolution remain poorly understood. Here we investigate three sets of whole HCV genomes in order to directly compare the evolution of whole HCV genomes at different biological levels: within- and among-hosts. We use a powerful Bayesian inference framework that incorporates both among-lineage rate heterogeneity and phylogenetic uncertainty into estimates of evolutionary parameters.

RESULTS:

Most of the HCV genome evolves at ~0.001 substitutions/site/year, a rate typical of RNA viruses. The antigenically-important E1/E2 genome region evolves particularly quickly, with correspondingly high rates of positive selection, as inferred using two related measures. Crucially, in this region an exceptionally higher rate was observed for within-host evolution compared to among-host evolution. Conversely, higher rates of evolution were seen among-hosts for functionally relevant parts of the NS5A gene. There was also evidence for slightly higher evolutionary rate for HCV subtype 1a compared to subtype 1b.

CONCLUSIONS:

Using new statistical methods and comparable whole genome datasets we have quantified, for the first time, the variation in HCV evolutionary dynamics at different scales of organisation. This confirms that differences in molecular evolution between biological scales are not restricted to HIV and may represent a common feature of chronic RNA viral infection. We conclude that the elevated rate observed in the E1/E2 region during within-host evolution more likely results from the reversion of host-specific adaptations (resulting in slower long-term among-host evolution) than from the preferential transmission of slowly-evolving lineages.